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National Journal of Maxillofacial Surgery
 
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Table of Contents
CASE REPORT
Year : 2016  |  Volume : 7  |  Issue : 1  |  Page : 105-107  

Aspergillosis associated with surgically assisted rapid maxillary expansion


Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Istanbul University, Istanbul, Turkey

Date of Web Publication19-Dec-2016

Correspondence Address:
Emine Akbas
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Istanbul University, Istanbul
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-5950.196145

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   Abstract 

Surgically assisted rapid palatal expansion (SARPE) is one of the most common orthognathic surgery operations for the treatment of maxillary transverse deficiencies. Although this operation is considered technically simple and has low complication rate, predisposing factors can complicate the postoperative period. In this case report, fistula formation and aspergillosis after SARPE operation were presented.

Keywords: Aspergillosis, functional endoscopic sinus surgery, surgically assisted rapid maxillary expansion


How to cite this article:
Cansiz E, Akbas E, Isler SC. Aspergillosis associated with surgically assisted rapid maxillary expansion. Natl J Maxillofac Surg 2016;7:105-7

How to cite this URL:
Cansiz E, Akbas E, Isler SC. Aspergillosis associated with surgically assisted rapid maxillary expansion. Natl J Maxillofac Surg [serial online] 2016 [cited 2017 Feb 22];7:105-7. Available from: http://www.njms.in/text.asp?2016/7/1/105/196145


   Introduction Top


Aspergillosis is the most common fungal infection of the paranasal sinuses and it usually occurs unilaterally in maxillary sinus.[1] On the other hand, Aspergillus infection of the maxillary sinus is relatively rare in nonimmunocompromised patients.[2],[3]

Transverse maxillary deficiency (TMD) is one of the most common skeletal dysplasias observed in clinical practice.[4] It can be treated with several techniques such as slow orthodontic expansion, rapid palatal expansion, and surgically assisted rapid palatal expansion (SARPE),[5] and the recommended technique for adult patients is SARPE because of limited osteogenic activity of palatal suture.[6]

The use of SARPE to treat TMD decreases adverse effects of orthodontic expansion such as lateral tipping of posterior teeth,[7] extrusion,[8] periodontal membrane compression, buccal root resorption,[9] alveolar bone bending,[10] fenestration of the buccal cortex,[11] palatal tissue necrosis,[12] inability to open the midpalatal suture, pain, and instability of the expansion.[13]

Although SARPE is a relatively easy and an effective operation, complication possibility due to technical sensitivity of surgical approach and patient's systemic condition must be considered.

In this case report, perforation-related fistula formation on inferior meatus and unilateral aspergillosis infection in maxillary sinus associated with SARPE, treated with functional endoscopic sinus surgery (FESS), were evaluated.


   Case Report Top


A 32-year-old systemically healthy woman with TMD was referred from the Orthodontics Department. After clinical examinations and consultations with the Orthodontics Department, SARPE was planned. The patient's medical history was unremarkable.

The patient was operated under general anesthesia with nasal endotracheal intubation. Before the surgical procedure, expansion device was activated. Following the full-thickness sulcular incision on the deepest level of the vestibular sulcus incision, the lateral surface of the maxilla was exposed with subperiosteal dissection. Nasal mucosa was elevated from the lateral nasal wall without any perforation, and bilateral corticotomy starting from the pyriform aperture to the pterygomaxillary fissure was performed. The medial walls of maxillary sinuses were separated bilaterally using guided osteotomes, and the palatal suture was separated using sharp chisel osteotome.

After splitting of segments, the expansion device was deactivated. The incision was closed primarily, and anterior nasal packs (Merocel standard dressing) were applied. The patient was discharged on the same day, and the 1st week of healing period was uneventful.

After 2 weeks, nasal defluxion complaint was reported. The patient consulted an ENT specialist and computed tomography revealed that the left middle meatus was congested with radiopaque substance [Figure 1]. Besides, endoscopic sinus examination showed that there was pus drainage from maxillary sinus to inferior meatus through fistula [Figure 2], and augmented amoxicillin with clavulanic acid (Augmentin, 1 g) was prescribed for 2 weeks to control sinusitis.
Figure 1: Computed tomography imaging of congested ostium and radiopaque appearance

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Figure 2: defluxion from fistula

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After 2 weeks, a granulation tissue in the maxillary sinus was observed during the endoscopic examination [Figure 3], and FESS was performed for decontamination of the maxillary sinus and correction of ostium function. Augmented amoxicillin with clavulanic acid (Augmentin, 1 g) was prescribed for 2 weeks again after FESS, and histopathological examination of the substance removed from the sinus revealed aspergillosis [Figure 4]a,[Figure 4]b,[Figure 4]c.
Figure 3: granulation formation

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Figure 4: (a) middle meatal antrostomy, (b) removal of substance located in the maxillary sinus, (c) postoperative appearance of the middle meatus

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After 3 weeks, it was observed that the ostium was functioning and there was no sign of aspergillosis. In 3 months, no recurrence was defined.


   Discussion Top


TMD is a major component of several malocclusions. Orthopedic and orthodontic forces are used generally to correct a TMD in young patients. Correction of TMD in adult patients is more challenging because of changes in osseous articulations of the maxilla with adjoining bones. Procedures described for the correction of TMD have conventionally been grouped into two categories as segmenting the maxilla during the Le Fort 1 osteotomy in a widened transverse dimension and SARPE. However, SARPE has become a common procedure and it has been considered as the procedure which has the lowest morbidity incidence, especially when compared with other orthognathic surgery procedures.[14]

SARPE allows clinicians to achieve satisfactory maxillary expansion in a skeletally mature patient and it decreases adverse effects of orthodontic expansion.[15] Although SARPE is a relatively simple procedure among other orthognathic surgery techniques, complications related with surgical technique and systemic condition of the patient must be considered.

In this case, fistula formation between the maxillary sinus and the inferior meatus occurred during osteotomy step of SARPE procedure, and the alteration of the sinus ventilation was complicated by the presence of aspergillosis. It is well-known data that the use of wide broad spectrum antibiotics in a long period can cause fungal infection.[16] However, unilateral aspergillosis cannot be considered only with antibiotherapy.

The middle meatus dysfunction and the operation trauma are other reasons of aspergillosis formation in this case. Although potential association between aspergillosis and SARPE was not described before in literature, it must be noted that SARPE causes perforation and fistula formation between the nasal cavity and maxillary sinuses. Consequently, this possibility can increase the risk of aspergillosis formation.


   Conclusion Top


Despite the frequent use of the procedure, only limited data on the prevalence of postoperative complications after SARPE are available in literature. On the other hand, some severe and unusual complications have been reported.[15]

It should be noted that fistula formation and meatus dysfunction related with SARPE operation cause fungal infection development. Careful preoperative planning and technical sensitivity is necessary to avoid complications.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

 
   References Top

1.
Chao TK. Triple discrete fungus balls of the paranasal sinuses. Otolaryngol Head Neck Surg 2004;131:1014-5.  Back to cited text no. 1
    
2.
Khongkhunthian P, Reichart PA. Aspergillosis of the maxillary sinus as a complication of overfilling root canal material into the sinus: Report of two cases. J Endod 2001;27:476-8.  Back to cited text no. 2
    
3.
Ashoor AA, Abu-Baker Y. Is the classical classification of aspergillosis of the paranasal sinuses to non invasive and invasive still valid or not? Bahrain Med Bull 2002;24:3.  Back to cited text no. 3
    
4.
Handelman CS. Nonsurgical rapid maxillary alveolar expansion in adults: A clinical evaluation. Angle Orthod 1997;67:291-305.  Back to cited text no. 4
    
5.
Verlinden CR, Gooris PG, Becking AG. Complications in transpalatal distraction osteogenesis: A retrospective clinical study. J Oral Maxillofac Surg 2011;69:899-905.  Back to cited text no. 5
    
6.
Babacan H, Sokucu O, Doruk C, Ay S. Rapid maxillary expansion and surgically assisted rapid maxillary expansion effects on nasal volume. Angle Orthod 2006;76:66-71.  Back to cited text no. 6
    
7.
Timms DJ. A study of basal movement with rapid maxillary expansion. Am J Orthod 1980;77:500-7.  Back to cited text no. 7
    
8.
Mommaerts MY. Transpalatal distraction as a method of maxillary expansion. Br J Oral Maxillofac Surg 1999;37:268-72.  Back to cited text no. 8
    
9.
Langford SR, Sims MR. Root surface resorption, repair, and periodontal attachment following rapid maxillary expansion in man. Am J Orthod 1982;81:108-15.  Back to cited text no. 9
    
10.
Isaacson RJ, Murphy TD. Some effects of rapid maxillary expansion in cleft lip and palate patients. Angle Orthod 1964;34:143-54.  Back to cited text no. 10
    
11.
Shetty V, Caridad JM, Caputo AA, Chaconas SJ. Biomechanical rationale for surgical-orthodontic expansion of the adult maxilla. J Oral Maxillofac Surg 1994;52:742-9.  Back to cited text no. 11
    
12.
Greenbaum KR, Zachrisson BU. The effect of palatal expansion therapy on the periodontal supporting tissues. Am J Orthod 1982;81:12-21.  Back to cited text no. 12
    
13.
Haas AJ. Long-term posttreatment evaluation of rapid palatal expansion. Angle Orthod 1980;50:189-217.  Back to cited text no. 13
    
14.
Bays RA, Greco JM. Surgically assisted rapid palatal expansion: An outpatient technique with long-term stability. J Oral Maxillofac Surg 1992;50:110-3.  Back to cited text no. 14
    
15.
Suri L, Taneja P. Surgically assisted rapid palatal expansion: A literature review. Am J Orthod Dentofacial Orthop 2008;133:290-302.  Back to cited text no. 15
    
16.
Krcméry V Jr., Matejicka F, Pichnová E, Jurga L, Sulcova M, Kunová A, et al. Documented fungal infections after prophylaxis or therapy with wide spectrum antibiotics: Relationship between certain fungal pathogens and particular antimicrobials? J Chemother 1999;11:385-90.  Back to cited text no. 16
    


    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4]



 

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